INTRODUCTION:
Glycidol is a viscous organic compound that belongs to the class of beta-oxyalcohols. Its reactivity is attributed to the epoxy moiety at beta position. The alcohol finds applications majorly in APIs, glycidyl esters and ethers, and in alkanolamines.
MANUFACTURE:
It is manufactured from 2-Chloro-1,3-propanediol in a catalyzed ring closure process. The unreacted reactant is removed by distillation.
|
Synonym |
Oxiran-2-ylmethanol 1,2-Epoxy-3-hydroxypropane |
|---|---|
|
CAS # |
556-52-5 |
|
EINECS # |
209-128-3 |
|
Molecular formula |
C3H6O2 |
|
Molecular weight |
74.08 |
|
Structure |
|
APPLICATION:
APIS:
- S-(-)-Atenolol (Beta-blocker)
- Guaifenesin (Expectorant)
- Indivir sulphate (Anti-retroviral)
- Leinamycin (Antibiotic)
- Levodropropizine (Antitussive)
- Propanolol (Beta-blocker)
INDUSTRIAL APPLICATIONS:
-
- The racemic product as such acts as:
- An epoxide building block
- A stabilizer in PVC compounding
- A stabilizer for natural oils and vinyl polymers
- A dye-levelling agent and a demulsifier
- A reactive diluent in coatings an RM in syntheses of polyurethanes and hyperbranched polyglycerols
- A gelation agent in solid propellants
INTERMEDIATE:
- Alkanolamines
- Polyglycerols
- Glycidyl methacrylate
- Glycidyl fatty acid esters
OTHER:
- Production of non-ionic surfactants based on fatty alcohols
SPECIFICATIONS:
|
Test |
Unit |
Specifications |
|---|---|---|
|
Appearance |
- |
Colorless transparent liquid |
|
Identification by IR |
- |
Should conform to the reference spectrum |
|
Identification by proton NMR |
- |
Should conform to the structure |
|
Specific Gravity |
g/cm3 |
1.10 -1.20 |
|
Moisture |
Wt % |
Max 0.5 |
|
Assay by GC |
% |
Min 97.0 |
|
Assay by titrimetry |
% |
Min 97.0 |
STORAGE:
Recommended storage temperature - 2° to 8°C Shipped under temperature-controlled conditions
PACKING:
50 kg /200 kg UN-approved HDPE drum
ICS offers Glycidol on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality & services will make ICS your supplier of choice. For additional information or Safety Data Sheet (SDS), please contact us at- info@itsusainc.com or Phone# 713-337-0152.
